
Neuro Prolotherapy for Sciatica London
Sciatica – pain, numbness, tingling or weakness radiating from the lower back through the buttock and down the leg – is one of the most debilitating pain presentations we see at Proback Clinic.
For many patients the structural compression driving their sciatica has been partially or substantially resolved – by time, physiotherapy or other treatment – yet the pain and neurological symptoms persist.
This is because the sciatic nerve has become chronically sensitised and continues to generate pain signals even after the original compression has reduced.
Neuro Prolotherapy directly addresses this neurogenic persistence – calming the hypersensitised nerve pathways along the full course of the sciatic nerve.
What Is Neuro Prolotherapy?
Neuro Prolotherapy – also known as Perineural Injection Therapy or PIT – is a treatment developed by New Zealand physician Dr John Lyftogt in which a very low concentration of natural dextrose solution is injected subcutaneously along the pathways of hypersensitised superficial nerves.
Rather than blocking or destroying the nerve signal, Neuro Prolotherapy works by calming the chronic neurogenic inflammation that is maintaining the pain – restoring normal nerve function rather than suppressing it temporarily.
It is completely natural, contains no steroids or synthetic drugs and has an excellent safety profile.
For a full overview of the treatment please visit our main Neuro Prolotherapy London page.
How Does It Help Sciatica Specifically?
When the sciatic nerve is compressed or irritated – by a disc herniation, piriformis syndrome, sacroiliac joint dysfunction or spinal stenosis – the nerve and its surrounding tissue become inflamed and hypersensitised.
Over time this sensitisation can become self-sustaining, meaning the nerve continues to generate pain signals even after the original mechanical cause has been reduced.
This is why many sciatica patients continue to suffer long after the disc bulge has receded on imaging.
Neuro Prolotherapy targets this neurogenic inflammation along the course of the sciatic nerve – from the lumbar nerve roots through the gluteal region, down the posterior thigh and into the lower leg – calming the sensitised pathways at multiple points simultaneously.
It is most powerful when combined with treatments that address the underlying mechanical cause.
Our typical approach for sciatica combines Spinal Decompression Therapy and Prolozone for the disc and nerve root with Neuro Prolotherapy along the peripheral sciatic pathway – addressing the condition from both ends simultaneously.
Suitable Presentations
- Chronic sciatica where pain and neurological symptoms persist despite resolution of the structural cause on imaging
- Sciatica that has partially responded to other treatments but not fully resolved
- Piriformis syndrome with sciatic nerve irritation
- Post surgical sciatica – where nerve sensitisation persists following disc or spinal surgery
- Sciatica associated with sacroiliac joint dysfunction
- Chronic leg pain, numbness or tingling with a nerve sensitisation component
Treatment and Sessions
Sessions target the superficial nerve pathways along the course of the sciatic nerve – typically the lumbar region, the sacral plexus area, the piriformis region and the posterior leg as appropriate to the specific symptom pattern.
Sessions take 20 to 40 minutes depending on the extent of the pathway treated.
Most patients require four to eight sessions for lasting results.
Book A Consultation For Only £110
Consultation includes a full clinical examination, standing X-rays or ultrasound imaging depending on your presentation, and a dedicated results appointment where your findings and a personalised treatment plan are explained in full before you commit to anything further.
We typically reply within 60 minutes during opening hours.
Why Choose Proback?
Proback Clinic is the official UK training partner of the European School of Prolotherapy – founded by Dr Stephen Cavallino MD.
Our Neuro Prolotherapy is delivered by certified practitioners with extensive clinical experience in perineural injection therapy.
We are based in Victoria, Central London – 5 minutes from Victoria station – with appointments available Monday to Friday 8.30am to 8pm and Saturday 9am to 3pm.
Call us on 0207 976 6648 or email victoria@proback.co.uk.
FAQs
This is very common.
Once the sciatic nerve has been compressed for a significant period it can remain sensitised and continue generating pain signals even after the original compression has reduced.
This is exactly what Neuro Prolotherapy addresses.
Yes - this is actually our preferred combined approach for sciatica at Proback.
Spinal Decompression addresses the disc level while Neuro Prolotherapy addresses the peripheral nerve pathway - treating the condition at both ends simultaneously.
Use the form below to book a consultation.
Consultation includes examination, X-ray (if required) and results.
We typically reply within 60 minutes during opening hours.
Award-Winning Treatments
Advanced Regenerative Medicine & Non-Surgical Treatments
Inside Proback
5 Minutes From London Victoria Station
Use the form below to book a consultation.
Consultation includes examination, X-ray (if required) and results.
We typically reply within 60 minutes during opening hours.
Accreditations




How To Find Us
4 Evelyn Mansions,
Carlisle Place, Victoria,
London SW1P 1NH
Opening Times
Weekdays 8.30am - 8pm
Saturday 9am - 3pm

020 7976 6648


























