How does prolozone work?

Prolozone acts on the tissues on 3 levels: First, an homeopathic form of medication is injected into the injured tissue, as well as nutrients which are required for healing, then oxygen in the form of ozone is injected providing the tissues with what it needs for healing.

Which area of the body can be treated with prolozone?

Most of the joints, including, back, neck, knees, ankles, shoulders, elbows, wrist, feet (plantar fascia) soft tissue area such as hamstrings, gluts, trigger points.

Are prolozone injections safe?

Prolozone is considered to be a safe and effective form of regenerative treatment for soft tissue (muscles), cartilage and joints. It is considered by many to be a great alternative to surgery.

How does it feel after a prolozone injection?

Most patients will feel a relief of 50% to 80% of their pain. If the injection was made into a joint, the gas can be heard when moving that joint. Some patients will feel the injection sites but usually the relief of pain is much greater than the soreness of the injection site.

Neuroprolotherapy

Neuroprolotherapy at Proback Advanced Back Care

FAQs

Neuroprolotherapy (also called neural prolotherapy or subcutaneous prolotherapy) involves injecting a dilute dextrose solution just beneath the skin along the path of peripheral nerves. The dextrose is thought to reduce neurogenic inflammation — the process by which irritated or compressed nerves release substance P and other neuropeptides that sustain pain. By calming this peripheral sensitisation, the nervous system gradually down-regulates its pain response, allowing tissues to heal in a more normal environment.

Almost any region supplied by peripheral nerves can be targeted. Common treatment areas include the neck and cervical spine, shoulder, elbow (including tennis and golfer's elbow), wrist and hand, thoracic spine, lower back and sacroiliac joints, hip and gluteal region, knee, shin and ankle, and the foot (including plantar fascia). It is particularly useful for post-surgical pain, nerve entrapment syndromes, and chronic regional pain that has not responded to other treatments.

Most patients need between 4 and 6 sessions, though this varies considerably. People with long-standing or complex conditions may require more. Because neuroprolotherapy works by gradually reducing neural inflammation, each treatment builds on the last — patients typically notice progressive improvement across the course of care rather than a single dramatic change.

Yes. The solution used is a highly dilute dextrose (sugar) and water preparation — a substance the body already produces and metabolises naturally. The injections are placed subcutaneously (just under the skin surface), so the risk of hitting vessels, nerves, or deeper structures is very low. Serious adverse events are extremely rare. It is safe to use in patients who cannot tolerate or have not benefited from steroid injections.

Many patients notice a significant reduction in pain within minutes of the injection — this is one of the hallmarks of neuroprolotherapy and helps confirm the nerves being treated are contributing to the patient's symptoms. There may be mild local soreness or a bruised feeling at the injection sites for 24–48 hours afterwards, but this typically resolves quickly. Unlike conventional prolotherapy, post-treatment discomfort is generally minimal because the injections are superficial.

Sessions are usually spaced 1–2 weeks apart. This interval allows the nervous system time to respond and consolidate the changes from each treatment. Once a patient reaches a stable level of improvement, the frequency is reduced and a maintenance plan (if needed) is discussed.

They share the same core agent — dextrose — but are distinct techniques with different mechanisms and depths of injection. Conventional prolotherapy targets ligaments, tendons, and joint structures at deeper tissue levels, aiming to stimulate a local healing response in connective tissue. Neuroprolotherapy is injected superficially (subcutaneously) along nerve pathways and targets peripheral neurogenic inflammation rather than structural repair. In practice, the two are often used together: neuroprolotherapy to calm the nervous system and reduce pain first, followed by deeper prolotherapy to address any underlying structural insufficiency.

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Patient Stories

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Sandra's Story

SYMPTOMS

Back Pain

TREATMENT

Spinal Decompression Therapy

Whilst working on her dad’s farm, 17 years ago, Sandra heard a loud crack in her back. Sandra had 6 steroid injections. She tried Physiotherapy, acupuncture and more but nothing helped. She kept getting worse and worse. The effect the pain was having spread beyond just Sandra. It was hurting everyone who loved her.